Research reveals the existence of a hidden ”pocket” on the surface of the main SARS-CoV-2 protein

With the continued emergence of new variants and the risk of new virus strains, the development of innovative therapies against SARS-CoV-2 remains a major public health challenge. Currently, the proteins located on the surface of the virus and/or involved in its replication are the preferred therapeutic targets, such as the Spike protein targeted by vaccines. … Read more

COVID-19 vaccination provides 60% to 94% protection against reinfection

Individuals previously infected with SARS-CoV-2, the virus that causes COVID-19, still benefit from vaccination and receive 60% to 94% protection against reinfection, depending on the variant. A new study led by Katrine Finderup Nielsen of the Statens Serum Institut, Denmark, reports these findings Nov. 22.nd in the open access journal PLOS medicine. During the recent … Read more

Hope for a new treatment on the horizon for the Zika virus

Bitten by an Aedes mosquito. This species can transmit diseases such as chikungunya, dengue and zika. … [+] Credit: NIAID (Photo by: IMAGE POINT FR/NIH/NIAID/BSIP //Universal Images Group via Getty Images) BSIP/Universal Images Group via Getty Images Researchers at Duke University, UC Berkeley, Purdue University and elsewhere have likely made a major breakthrough in the … Read more

The biological properties of the SARS-CoV-2 E protein in the context of HIV-1

In a recent study published in Retrovirologyresearchers assessed the effectiveness of SARS-CoV (Severe Acute Respiratory Syndrome) and SARS-CoV-2 envelope (E) proteins against human immunodeficiency virus (HIV)-1. Study: SARS-CoV-2 and SARS-CoV envelope proteins potently reduce the infectivity of human immunodeficiency virus type 1 (HIV-1). Image credit: Corona Borealis Studio/Shutterstock Background Viroporins are ion channels expressed by … Read more

Virus warning while smearing mosquitoes with insect repellent

Geelong is bracing for a possible jump in Ross River virus cases following an explosion in the local mosquito population. Squadrons of the pesky insects buzz along coastal and riverine communities after weeks of heavy rains that created perfect breeding conditions. Mosquitoes can transmit numerous diseases, including Ross River, Barmah Forest virus, Japanese encephalitis virus, … Read more

Rutgers scientists are developing a new approach to effectively stop viral infections

Rutgers scientists have developed a new approach to stopping viral infections: a so-called live attenuated, replication-defective DNA virus vaccine that uses a compound known as centanamycin to generate an altered virus for vaccine development. The method was tested to produce a weakened or “weakened” version of a mouse cytomegalovirus, a common virus, that has been … Read more

Scientists investigate isolation of bat sarbecovirus in Japan

In a recent study published in Emerging infectious diseasesresearchers conducted bat sarbecovirus isolation experiments using Horned Rhinolophus bats from different regions in Japan that were phylogenetically situated in the same cluster of viruses associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Study: Isolation of Bat Sarbecoviruses, Japan. Image Credit: Independent Birds/Shutterstock Highly pathogenic human … Read more

How gut microbes influence the immune response to SARS-CoV-2

An article published in Critical Assessments in Food Science and Nutrition journal reviews the role of the gut microbiota in shaping the host immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Study: Gut microbiome and antiviral immunity in COVID-19. Image credit: Design_Cells / Shutterstock Background SARS-CoV-2, the causative agent of the 2019 coronavirus … Read more

SARS-CoV-2 infection causes reactivation of latent viruses in people with chronic fatigue syndrome

COVID-19 reactivated viruses that had become latent in cells from previous infections, especially in people with chronic fatigue syndrome, also known as ME/CFS. This is the conclusion of a study by Linköping University in Sweden. The results, published in Frontiers in immunologycontribute to our knowledge of the causes of the disease and the prospects of … Read more

Emergency rooms across Ohio full as three viruses swell together

Emergency rooms across Ohio are full, emergency care is on lockdown, and three viruses causing the problems have not been pushed back. COVID-19. “We are seeing record high volumes in our emergency room, our urgent care and our hospitals in general,” said Dr. Patty Manning, chief of staff at Cincinnati Children’s Hospital. Manning said they … Read more