New machine learning tool discovers mutational signature linking bladder cancer to smoking

Researchers at the University of California at San Diego have discovered for the first time a pattern of DNA mutations that links bladder cancer to tobacco smoking. The discovery was made possible thanks to a powerful new machine learning tool the team developed to find patterns of mutations caused by carcinogens and other DNA-altering processes. … Read more

Clean living linked to lower mortality in former smokers

An important message for former smokers: you can overcome a history of vice through virtue. Researchers have found that people with a history of smoking who exercise regularly, eat nutritious foods and maintain a healthy weight reduce their risk of premature death by nearly 30% compared to those who don’t adopt such good habits. “Being … Read more

AI-guided tools pinpoint immune cell booster and protective genetic factor for esophageal cancer

Esophageal adenocarcinoma (EAC) is a cancer that affects the mucus-secreting glands of the lower esophagus; the tube that connects the throat to the stomach. It is the most common form of esophageal cancer and is often preceded by Barrett’s metaplasia (BE), a damaging change in cells lining the esophagus. While the cause of EAC remains … Read more

Teens start vaping and using weed and lose interest in booze and other drugs

Photo: Shutterstock (Shutterstock) Teens have been using fewer drugs in recent decades, with two important exceptions, new research suggests this week. Reported levels of drug use have declined for most substances since the early 1990s, the study found, but rates of cannabis use and vaping have risen. The findings also indicate that having less free … Read more

Teens start vaping and using weed and lose interest in booze and other drugs

Photo: Shutterstock (Shutterstock) Teens have been using fewer drugs in recent decades, with two important exceptions, new research suggests this week. Reported levels of drug use have declined for most substances since the early 1990s, the study found, but rates of cannabis use and vaping have risen. The findings also indicate that having less free … Read more

Research shows that 44% of global cancer deaths are preventable

A recent study published in The Lancet has estimated the global cancer burden caused by behavioral, environmental, occupational and metabolic risk factors. The research results show that behavioral risk factors are a major contributor to the global cancer burden in 2019. Moreover, the largest induction of metabolic risk factors has been observed between 2010 and … Read more

Bill Ackman says fast food chains are an inflationary shield. Here are two he likes, and one he just sold.

A cautious session is imminent on Tuesday, following the worst hit since June for major indices. That’s because an increasing number of investors are watching the Fed move from rate hikes to a major task in the face of persistently high inflation and a global growth slump. We’ll find out on Friday when Fed Chair … Read more

Smoking and the risk of contracting SARS-CoV-2 and COVID-19

Smoking increases the risk of respiratory infections, such as the common cold, flu, pneumonia and tuberculosis. Smoking can also contribute to complications of coronavirus disease 2019 (COVID-19). Study: Tobacco product use and the risks of SARS-CoV-2 infection and COVID-19: current insights and recommendations for future research. Image credit: wavebreakmedia/Shutterstock.com Background Numerous previous studies have confirmed … Read more

Researchers assess lutein nanodiscs against ultraviolet light-induced retinal damage

In a recent study published in the Borders magazine, researchers assessed the role of lutein nanodiscs against ultraviolet (UV) light-induced damage to retinal cells. Study: Lutein nanodiscs protect human retinal pigment epithelial cells from UV light-induced damage. Image credit: Monet_3k/Shutterstock Age-related macular degeneration (AMD) is responsible for 8.7% of blindness worldwide. Studies have attributed this … Read more

Generation of Live Attenuated Influenza A Virus Vaccine Using PROTAC Technology

A promising strategy to reduce the impact of viral infectious diseases, such as flu, is to use attenuated, live viruses as vaccines. However, the usefulness of traditional live attenuated virus vaccines is often limited by suboptimal immunogenicity, safety concerns, or cumbersome manufacturing processes and techniques. In addition, immune escape due to rapid viral evolution presents … Read more