Do previously infected people still benefit from vaccination against COVID-19?

In a recent study published in PLOS medicine, researchers determined the vaccine effectiveness (VE) of the primary vaccination course for coronavirus disease 2019 (COVID-19). They determined VE against reinfection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), COVID-19-related hospitalization and mortality. In this way, the researchers assessed the effect of time since vaccination during the … Read more

Research reveals the existence of a hidden ”pocket” on the surface of the main SARS-CoV-2 protein

With the continued emergence of new variants and the risk of new virus strains, the development of innovative therapies against SARS-CoV-2 remains a major public health challenge. Currently, the proteins located on the surface of the virus and/or involved in its replication are the preferred therapeutic targets, such as the Spike protein targeted by vaccines. … Read more

COVID-19 vaccination provides 60% to 94% protection against reinfection

Individuals previously infected with SARS-CoV-2, the virus that causes COVID-19, still benefit from vaccination and receive 60% to 94% protection against reinfection, depending on the variant. A new study led by Katrine Finderup Nielsen of the Statens Serum Institut, Denmark, reports these findings Nov. 22.nd in the open access journal PLOS medicine. During the recent … Read more

Myocarditis after COVID vaccination is rare, but more common in younger men

In a recent study published in the Journal of the Canadian Medical Association, researchers observed the incidence of myocarditis after messenger ribonucleic acid (mRNA)-based vaccination against coronavirus disease 2019 (COVID-19). In addition, they compared their estimates to expected rates based on the historical rates assessed before the COVID-19 vaccine rollout in British Columbia (BC), Canada. … Read more

The biological properties of the SARS-CoV-2 E protein in the context of HIV-1

In a recent study published in Retrovirologyresearchers assessed the effectiveness of SARS-CoV (Severe Acute Respiratory Syndrome) and SARS-CoV-2 envelope (E) proteins against human immunodeficiency virus (HIV)-1. Study: SARS-CoV-2 and SARS-CoV envelope proteins potently reduce the infectivity of human immunodeficiency virus type 1 (HIV-1). Image credit: Corona Borealis Studio/Shutterstock Background Viroporins are ion channels expressed by … Read more

Increased incidence and risk of a new diagnosis of diabetes after COVID-19

In a recent study published in the journal BMC medicineresearchers estimate the prevalence of new diabetes after coronavirus disease 2019 (COVID-19). Despite the numerous vaccines and antiviral therapies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the COVID-19 pandemic continues to threaten public health and the economy, with more than 634 million cases and more … Read more

Rutgers scientists are developing a new approach to effectively stop viral infections

Rutgers scientists have developed a new approach to stopping viral infections: a so-called live attenuated, replication-defective DNA virus vaccine that uses a compound known as centanamycin to generate an altered virus for vaccine development. The method was tested to produce a weakened or “weakened” version of a mouse cytomegalovirus, a common virus, that has been … Read more

Scientists investigate isolation of bat sarbecovirus in Japan

In a recent study published in Emerging infectious diseasesresearchers conducted bat sarbecovirus isolation experiments using Horned Rhinolophus bats from different regions in Japan that were phylogenetically situated in the same cluster of viruses associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Study: Isolation of Bat Sarbecoviruses, Japan. Image Credit: Independent Birds/Shutterstock Highly pathogenic human … Read more

How gut microbes influence the immune response to SARS-CoV-2

An article published in Critical Assessments in Food Science and Nutrition journal reviews the role of the gut microbiota in shaping the host immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Study: Gut microbiome and antiviral immunity in COVID-19. Image credit: Design_Cells / Shutterstock Background SARS-CoV-2, the causative agent of the 2019 coronavirus … Read more

Comparison of post-COVID-19 symptoms two years after SARS-CoV-2 infection

In a recent study published in JAMA network openedresearchers compared the presence of post-coronavirus disease 2019 (COVID-19) symptoms in hospitalized and non-hospitalized patients in Spain. Study: Post-COVID-19 Symptoms 2 Years After SARS-CoV-2 Infection in Hospitalized vs Non-Hospitalized Patients. Image credit: TZIDO SUN/Shutterstock In addition, the researchers identified potential risk factors associated with developing post-COVID-19 symptoms … Read more