Unexpected decline in cognitive performance after epilepsy surgery

In severe epilepsy, surgical intervention is often the only cure – usually with great success. Although neuropsychological performance can recover in the long term after successful surgery, unexpected declines in cognitive performance occur in rare cases. Researchers at the University of Bonn have now been able to show which patients are at particularly high risk. … Read more

Low-dose CT screening improves the survival rate of lung cancer patients

Diagnosing lung cancer at an early stage with low-dose computed tomography (CT) screening dramatically improves cancer patients’ survival rates over a 20-year period, according to a large-scale international study being presented by Mount Sinai researchers at the annual meeting of the Radiological Association of North America. The results show that patients with early-stage lung cancer … Read more

The vaginal microbiome through the lens of systems biology

The human organism is a complex ecosystem of coexisting microbiomes, including those in the gut, skin and vagina in women. These play a crucial role in health and disease. However, there is still much to learn about them. A new article recently published online in Trends in microbiology magazine discusses the systems biology approach to … Read more

Almond consumption may keep extra pounds at bay, study says

Weight loss is never an easy nut to crack, but according to new research from the University of South Australia, a handful of almonds can keep extra pounds at bay. Investigating how almonds may affect appetite, researchers found that a snack of 30-50 grams of almonds could help people reduce the number of kilojoules they … Read more

Study provides more accurate tool to stratify patients with HER2-positive breast cancer

Patients with a type of breast cancer called HER2-positive are less likely to survive if their initial treatment doesn’t completely eradicate the tumor and they have high levels of immune cells called tumor-infiltrating lymphocytes with residual disease. Dr Federica Miglietta told the 13e European Breast Cancer Conference that normally tumor-infiltrating lymphocytes (TILs) help the body’s … Read more

Rutgers scientists are developing a new approach to effectively stop viral infections

Rutgers scientists have developed a new approach to stopping viral infections: a so-called live attenuated, replication-defective DNA virus vaccine that uses a compound known as centanamycin to generate an altered virus for vaccine development. The method was tested to produce a weakened or “weakened” version of a mouse cytomegalovirus, a common virus, that has been … Read more

IESC transplant can restore the gut barrier after stroke and improve outcomes

Stroke is a leading cause of death, dementia and severe long-term disability. According to the American Heart Association, stroke patients also have a greater risk of depression, which has a negative effect on functional and cognitive recovery. The only Food and Drug Administration (FDA)-approved drug to treat stroke, a type of recombinant tissue plasminogen activator, … Read more

Kessler and BrainQ are collaborating on a national trial of a breakthrough device to improve stroke recovery

Researchers from the Kessler Foundation and the Kessler Institute for Rehabilitation (collectively, “Kessler”) are enrolling participants in a national trial of a breakthrough device to improve recovery after stroke. Kessler locations in West Orange and Saddle Brook, NJ, are among 20 US locations participating in the EMAGINE Stroke Recovery Trial, which combines therapeutic exercise with … Read more

Diet change may be a key to improving colon cancer treatment

A change in diet may be key to improving colon cancer treatment, finds a new study from the University of Michigan Rogel Cancer Center. Cancer cells need nutrients to survive and grow. One of the most important nutrient-sensing molecules in a cell is called mTORC1. Often referred to as a master regulator of cell growth, … Read more

Researchers discover new therapeutic vulnerability in breast cancer that is resistant to hormone therapy

For patients with estrogen receptor (ER) positive breast cancer, the development of the so-called Y537S mutation indicates that their disease has taken an aggressive course and may be becoming resistant to endocrine therapy. Now a preclinical study, led by researchers at UT Southwestern Medical Center, suggests that a class of new drugs already in clinical … Read more