AI-guided tools pinpoint immune cell booster and protective genetic factor for esophageal cancer

Esophageal adenocarcinoma (EAC) is a cancer that affects the mucus-secreting glands of the lower esophagus; the tube that connects the throat to the stomach. It is the most common form of esophageal cancer and is often preceded by Barrett’s metaplasia (BE), a damaging change in cells lining the esophagus. While the cause of EAC remains … Read more

Ketamine shows promise for rare disorder linked to autism

Ketamine may be an effective treatment for children with activity-dependent neuroprotective protein syndrome (ADNP), a rare genetic disorder associated with intellectual disability and autism spectrum disorder. ADNP syndrome, also known as Helsmoortel-Van Der Aa syndrome, is caused by mutations in the ADNP gene. Studies in animal models suggest that low-dose ketamine increases ADNP expression and … Read more

Possible cause of racial inequality in infants with congenital heart disease discovered

Race was already known to matter when it came to the health outcomes of infants with congenital heart disease (CHD), the most common birth defect, affecting 1 in 100 live births. In the first year of life, African Americans are 1.4 times more likely and Hispanics 1.7 times more likely to die from CHD than … Read more

Children hospitalized with COVID-19 often experience neurological complications

Doctors at the Monroe Carell Jr. Children’s Hospital in Vanderbilt have found another reason to vaccinate children against COVID-19: to reduce the chance of neurological complications caused by the virus. “COVID-19 and Acute Neurological Complications in Children,” a study of more than 15,000 children hospitalized with COVID-19 at 52 children’s hospitals over a two-year period, … Read more

Researchers find an epigenetic signature linked to MIS-C

MADRID, Spain-For pediatric specialists, one of the riddles of SARS-COV-2 infection was the greater resistance of pediatric patients against experiencing severe COVID-19 symptoms and the presence, in a small percentage, of the so-called multi-system Inflammatory syndrome in children (MIS-C) or pediatric multi system syndrome, a serious condition that requires intensive care in 60% of the … Read more