Sleep loss damages immune genes, causes inflammation, study says

CNN — Chronic sleep deprivation in a small group of healthy adults increased the production of immune cells linked to inflammation, while also altering the DNA of the immune cells, a new study finds. “Not only was the number of immune cells increased, but they can be wired and programmed differently at the end of … Read more

AI-guided tools pinpoint immune cell booster and protective genetic factor for esophageal cancer

Esophageal adenocarcinoma (EAC) is a cancer that affects the mucus-secreting glands of the lower esophagus; the tube that connects the throat to the stomach. It is the most common form of esophageal cancer and is often preceded by Barrett’s metaplasia (BE), a damaging change in cells lining the esophagus. While the cause of EAC remains … Read more

Azerbaijan Thalassemia Center and BGI collaborate to improve thalassemia screening in Azerbaijan

at 6e In September 2022, the Azerbaijan Thalassemia Center and BGI held a virtual signing ceremony to seal a cooperation agreement. The partnership aims to improve thalassemia screening in Azerbaijan through genetic engineering. In early 2021, on the occasion of the announcement “Prevention and Control of Global Hemoglobinopathies”, the BGI Poverty Prevention and Control Panel … Read more

Duke researchers identify chlamydia’s stealthy cloaking device

Chlamydia, the leading cause of sexually transmitted bacterial infections, evades detection and elimination in human cells through a cloaking device. But Duke University researchers have grabbed the hem of that invisibility cloak and now hope they can pull it apart. To enter the cell and reproduce peacefully, many pathogenic bacteria, including Chlamydia, envelop a piece … Read more

Complete genetic architecture of racial cancer gene mutations in human tumors discovered

Newswise – Researchers from the Johns Hopkins Kimmel Cancer Center, three other cancer centers and the Johns Hopkins Bloomberg School of Public Health have compiled a comprehensive genetic architecture atlas for mutated RAS genes in human cancers. Their four-year study of the RAS family — including the KRAS, NRAS and HRAS genes mutated in about … Read more

Study Provides Comprehensive View of Genomics of All Childhood ALL Subtypes

Scientists have created a roadmap of the genetic mutations present in the most common childhood cancer, acute lymphoblastic leukemia (ALL). The St. Jude Children’s Research Hospital study is the first to provide a comprehensive overview of the genomics of all subtypes of ALL. The work serves as a fundamental guide for physicians and scientists to … Read more

Researchers reveal the role of the CHAMP1 gene in neuronal development

Newswise – Intellectual disability affects approximately 2-3% of the world’s population. Scientists understand the genes associated with intellectual disability, but how the mutations of these genes cause this developmental disability remains largely unknown. As a result, effective therapeutic interventions are lacking. Now, a research group led by two Tohoku University researchers has discovered the role … Read more

Doubles don’t just look alike – they look alike

It is said that you cannot judge a book by its cover. But when it comes to faces, it turns out that similar features are more than just skin-deep. Doubles don’t just look alike, they’re the same, scientists discovered after an in-depth study of the genetics and behavior of unrelated people who share uncanny facial … Read more

Researchers assess lutein nanodiscs against ultraviolet light-induced retinal damage

In a recent study published in the Borders magazine, researchers assessed the role of lutein nanodiscs against ultraviolet (UV) light-induced damage to retinal cells. Study: Lutein nanodiscs protect human retinal pigment epithelial cells from UV light-induced damage. Image credit: Monet_3k/Shutterstock Age-related macular degeneration (AMD) is responsible for 8.7% of blindness worldwide. Studies have attributed this … Read more

Heart failure stems from mutations in several genes, study finds

Heart failure is a common and devastating condition for which there is no cure. Many cardiomyopathies – conditions that make the heart difficult to pump blood, such as dilated cardiomyopathy (DCM) and arrhythmogenic cardiomyopathy (ACM) -; can lead to heart failure, but treatments for patients with heart failure do not take into account these different … Read more