DNA Metagenomic Analyzes of Clinical Samples from Monkeypox Virus Infected Individuals

In a recent study posted to the bioRxiv*server, researchers analyzed Monkeypox virus (MPXV) genomic sequences obtained from 18 patients who contracted MPXV infection between June and July 2022. Study: Sequencing of Monkeypox virus from infected patients reveals viral genomes with APOBEC3-like editing, gene inactivation and bacterial agents of skin superinfection. Image Credit: Kateryna Kon/Shutterstock Background … Read more

Scientists develop a rapid, highly sensitive method for detecting SARS-CoV-2 in wastewater

Wastewater-based epidemiology (WBE) has proven to be an excellent tool to understand the spread of SARS-CoV-2 in communities. It is now used in multiple areas around the world to track the prevalence of the virus and serves as a proxy for determining the status of COVID-19. Of particular note, WBE can be used to estimate … Read more

New machine learning tool discovers mutational signature linking bladder cancer to smoking

Researchers at the University of California at San Diego have discovered for the first time a pattern of DNA mutations that links bladder cancer to tobacco smoking. The discovery was made possible thanks to a powerful new machine learning tool the team developed to find patterns of mutations caused by carcinogens and other DNA-altering processes. … Read more

DNA nets effectively target the spike protein and detect the COVID-19 virus at very low levels

Tiny nets woven from strands of DNA can entangle the spike protein of the virus that causes COVID-19, illuminating the virus for a quick but sensitive diagnostic test — as well as preventing the virus from infecting cells, causing a new possible route to antiviral drugs is opened. treatment, according to a new study. Researchers … Read more

AI-guided tools pinpoint immune cell booster and protective genetic factor for esophageal cancer

Esophageal adenocarcinoma (EAC) is a cancer that affects the mucus-secreting glands of the lower esophagus; the tube that connects the throat to the stomach. It is the most common form of esophageal cancer and is often preceded by Barrett’s metaplasia (BE), a damaging change in cells lining the esophagus. While the cause of EAC remains … Read more

Study reveals how air pollution can cause lung cancer in individuals with no smoking history

Recent research by a team of scientists from The Francis Crick Institute, presented at the European Society for Medical Oncology (ESMO) 2022 Congress in Paris, reveals a link between air pollution and lung cancer in non-smokers. The research was funded by Cancer Research UK and is part of the TRACERx Lung Study, which aims to … Read more

How can Legionella pneumophila spread through the hot water pipes of homes and office buildings?

In a recent study published in the International Journal of Hygiene and Environmental Healthresearchers are investigating the transmission of the causative agent of legionellosis, Legionella pneumophila, through hot water pipes in commercial and residential buildings. Study: Hot water pipes in homes and office buildings have a clear risk of contamination with Legionella pneumophila. Image credit: … Read more

Researchers assess the epidemiology, clinical character, treatment and prevention of human monkeypox

In a recent review published in Clinical Immunologyresearchers have assessed the epidemiology, clinical character, treatment, and prevention of human monkeypox (MPX). Study: The resurgence of a neglected orthopox virus: immunological and clinical aspects of monkeypox virus infections over the past six decades. Image credit: ART-ur/Shutterstock Background and epidemiology The MPX virus (MPXV) was first isolated … Read more

Neurological manifestations associated with monkeypox infection

As the 2019 coronavirus disease (COVID-19) transitions into an endemic disease, the widespread transmission of monkeypox virus has become a new public health threat. Previously, monkeypox virus was mainly found in endemic countries in West and Central Africa. However, in April of this year, the virus suddenly started to spread rapidly, mainly among men who … Read more