AI-guided tools pinpoint immune cell booster and protective genetic factor for esophageal cancer

Esophageal adenocarcinoma (EAC) is a cancer that affects the mucus-secreting glands of the lower esophagus; the tube that connects the throat to the stomach. It is the most common form of esophageal cancer and is often preceded by Barrett’s metaplasia (BE), a damaging change in cells lining the esophagus. While the cause of EAC remains … Read more

Novel antiviral mechanism of action for an FDA-approved thiopurine known as 6-thioguanine

In a recent study published in PLoS pathogensresearchers described a novel antiviral mechanism of action for an FDA (food and drug administration) approved thiopurine known as 6-thioguanine (6-TG). Study: Thiopurins inhibit the processing and uptake of the coronavirus Spike protein in progeny virions. Image Credit: Bacsica/Shutterstock Background The pandemic of severe acute respiratory syndrome coronavirus … Read more