Reduction of glycemia in type 2 diabetes – glycemic results

Supported by a grant (U01DK098246) from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) from the National Institutes of Health (NIH); a U34 planning grant (U34-DK-088043) for trial planning from the NIDDK; funding for the first planning meeting related to the U34 proposal of the American Diabetes Association; the National Heart, Lung and Blood Institute; the Center for Disease Control and Prevention; Department of Veterans Affairs resources and facilities; grants (P30 DK017047, P30 DK020541-44, P30 DK020572, P30 DK072476, P30 DK079626, P30 DK092926, U54 GM104940, UL1 TR000170, UL1 TR000439, UL1 TR000445, UL1 TR00110823, UL1 TR0011081, UL1 TR00110100, TR002378, UL1 TR002489, UL1 TR002529, UL1 TR002535, UL1 TR002537, UL1 TR002541, and UL1 TR002548 from the NIH; educational materials from the National Diabetes Education Program; and donated medications and supplies from Becton Dickinson, Bristol Myers Squibb, Merck, Novo Roche Diagnostics and Sanofi.

Disclosure forms provided by the authors are available with the full text of this article on NEJM.org.

The members of the writing committee (David M. Nathan, MD, John M. Lachin, Sc.D., Ashok Balasubramanyam, MD, Henry B. Burch, MD, John B. Buse, MD, Nicole M. Butera, Ph. D , Robert M. Cohen, MD, Jill P. Crandall, MD, Steven E. Kahn, MB, Ch.B., Heidi Krause-Steinrauf, MS, Mary E. Larkin, RN, Neda Rasouli, MD, Margaret Tiktin , DNP, Deborah J. Wexler, MD, and Naji Younes, Ph.D.) assume responsibility for the overall content and integrity of this article.

The contents of this article are the sole responsibility of the authors and do not necessarily represent the official views of the National Institutes of Health.

A data sharing statement from the authors is available with the full text of this article at NEJM.org.

We would like to thank the participants who, thanks to their loyal efforts, made this trial possible.

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