Second place at the Olympics last summer and again at the 800m World Championships last month, in Birmingham her and the 30,000 at Alexander Stadium was expected to be her place on the top step of the podium.
But instead of being ousted by Athing Mu as she was in both Tokyo and Eugene, Mary Moraa this time proved her nemesis in one of the most bizarre running races of recent years.
The Kenyan set an electric opening lap, finishing a second 200m at just 12.9 seconds, leaving her latest rivals in her wake.
Realizing she’d gone almost two or three seconds too fast, she slowed down and let the entire field pass her as she approached the bell.
With Moraa looking completely exhausted, the race resembled Hodgkinson’s and she duly took to the front and started her kick from 200 yards.
But the Kenyan found a new lease of life to pass the 20-year-old on the straight and win comfortably as the English athlete had to make do with second place again.
Laura Muir took the bronze medal before going into the 1500 meters final on Sunday, where she is the favorite for gold.
Hodgkinson described himself as “frustrated” by the result. She said: “I’m not sure what happened. It went so fast, maybe I could have been more patient with myself. But I gave it my all and unfortunately I got away with the silver… again.
“I’m disappointed. There are positives, but still no gold. I’m still smoking until I’m on top of that podium. It’s not. Hopefully another time.”
The 20-year-old has a third and final shot at gold over two laps of the track at the European Championships in Munich.
There was a redemption of sorts Zharnel Hughes in the ensuing 200 meters. Four years ago, he had celebrated what he thought was gold on the Gold Coast, but was disqualified for hindering Jereem Richards.
Richards had entered the race comfortably fastest in the field, winning easily in a time of 19.80 at the Games, while Hughes, a one-time training partner of Usain Bolt, took silver in the best of 20.12 of a season.
There were two English medals in the men’s pole vault as Adam Hague finished second and Harry Coppell third as Australia’s Kurtis Marschall,
And in the final race of the evening, Elaine Thompson-Herah, like Richards, ran a Games record 20.02s to complete the sprint double for Jamaica.